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476 EDTA Chelation Therapy References, Page 1 of 2



  1. Ahrens FA and Aronson AL: A comparative study of the toxic effects of calcium and chromium chelates of ethylenediaminetetraacetate in the dog. Toxic Appl Pharmac 18:10, 1971.

  2. Ahrens FA and Aronson AL: Toxicity of calcium ethylenediaminetetraacetate in dogs. Fed Proc Fedn Am Soc Exp Biol 27:1401, 1968.

  3. Adams WJ and McGee CT: Chelation therapy: a survey of treatment outcomes and selected socio-medical factors. J Adv Med 5(3):189, 1992.

  4. Agerty HA: Lead poisoning in children. Medical Clinics of North America. (36):1587, 1952.

  5. Ahrens FA and Aronson AL: Comparative study of the toxic effects of calcium chelates of ethylenediaminetetraacetate in the dog. Tox Appl Pharmocol (18)1:10 1971.

  6. Alfthan G, Pikkarainen J, Huttunen JK, Puska P: Association between cardiovascular death and myocardial infarction and serum selenium in a matched- pair longitudinal study. Lancet 2(8291):175, 1982.

  7. Allen AC: The Kidney Grune and Stratton, N.Y., p. 329, 1962.

  8. AItmann J, Wakim KG and Winkelmann RK: Effects of edathamil disodium on the kidney. J Invest Dermatol (38): 215, 1962.

  9. Angle CR and McIntire MS: Lead poisoning during pregnancy. Fetal tolerance of calcium disodium edetate . Am J Dis Child 108:436, 1964.

  10. Ames BN: Dietary carcinogens and anticarcinogens. Science 221:1256, 1983.

  11. Aronov DM: First experience with the treatment of atherosclerosis patients with calcinosis of the arteries with trilon-B (disodium salt of EDTA). (Russ, Moscow) Klin Med 41:19, 1963.

  12. Aronson AL and Ahrens FA: The mechanism of renal transport and excretion of ethylenediaminetetraacetate with interspecies comparison. Toxic Appl Pharmac 18:1, 1971.

  13. Aronson AL and Hammond PB: Effect of two chelating agents on the distribution and excretion of lead. J Pharmacol Exp Ther 146:241-251, 1964.

  14. Aronson AL, Hammond PB and Strafuss AC: Studies with calcium ethylenediaminetetraacetate in calves; toxicity and use in bovine lead poisoning. Toxicol Appl Pharmacol 12:337-349, 1968.

  15. Atherosclerosis and auto oxidation of cholesterol, editorial. Lancet ii:964, 1980.

  16. Batchelor TM, McCall M and Mosher RM: Potassium dieresis induced by edathamil disodium. JAMA 187:305, 1964.

  17. Bates GW, Billups C and Saltman P: The kinetics and mechanism of iron (III) exchange between chelates and transferrin. II. The presentation and removal with ethylenediaminetetraacetate. J Biol Chem 242:2816, 1967.

  18. Batuman V, Landy E, Maesaka JK, Wedeen RP: Contribution of lead to hypertension with renal impairment .N EngI J Med 309(1):17, 1983.

  19. Batuman V, Maesaka JK, Haddad B, et al: The role of lead in gout nephropathy. N.E.J.M. (304)9:520, 1981.

  20. Bauer RO, Rullo FR, Spooner C, et al: Acute and subacute toxicity of ethylene diamine tetraacetic acid (EDTA) salts. Federation Proc (11): 321, 1952.

  21. Bechtel JT, White JE and Estes EH Jr: The electrocardiographic effects of hypocalcemia induced in normal subjects with edathamil disodium. Circulation 13:837, 1956.

  22. Belknap EL: EDTA in the treatrment of lead poisoning. Indust Med & Surg (21):305,1952.

  23. Berkman N, Michaeli Y, Or R and Eldor A: EDTA dependent pseudothrombocytopenia: a clinical study of 18 patients and a review of the literature. Am J Hematol 36:195, 1991.

  24. Bessman SP, Ried H and Rubin M: Treatment of lead encephalopathy with calcium disodium versenate. Ann Med Soc DC 21:312, 1952.

  25. Bhat RK, et a!: Trace elements in hair and environmental exposure. Sci Total Environ 22(2):169, 1982.

  26. Birk RE and Rupe CE: The treatment of systemic sclerosis with disodium EDTA, pyridoxine and reserpine. Henry Ford Hosp Med Bull 14:109, 1966.

  27. Birk RE and Rupe CE: Systemic sclerosis. Fourteen cases treated with chelation (disodium EDTA) and/or pyridoxine, with comments on the possible role of altered tryptophan metabolism in pathogenesis. Henry Ford Hosp Med Bull 10:523, 1962.

  28. Bjorksten J: The cross-linkage theory of aging as a predictive indicator. Rejuvenation 8:59, 1980.

  29. Bjorksten J: Possibilities and limitations of chelation as a means for life extension. Rejuvenation 8:67, 1980.

  30. Blake DR, Hall ND, Bacon PA, Dieppe PA, Halliwell B, Gutteridge JM: The importance of iron in rheumatoid disease. Lancet :1142, 1981.

  31. Blake DR, Hall ND, Bacon PA, Dieppe PA, Halliwell B, Gutteridge JMC: Effect of a specific iron chelating agent on animal models of inflammation. Ann Rheum Dis 42:89, 1983.

  32. Bland JS: The utility of hair analysis: A reevaluation. J Holistic Medicine 5(1):16, 1983.

  33. Blumer W, Reich T: Leaded gasoline – cause of cancer. Environmental International 3:465, 1980.

  34. Blumer W and Cranton EM: Ninety percent reduction in cancer mortality after chelation therapy with EDTA. J Adv Med 2:183, 1989.

  35. Bolick LE and Blankenhorn DH: A quantitative study of coronary arterial calcification. Am J Path 39:511, 1961.

  36. Boyle AJ, Jasper JJ, McCormick H, et al: Studies in human and induced atherosclerosis employing – (EDTA). Bull Swiss Acad Med Sci 13:408, 1957.

  37. Boyle M, Wegria R, Cathcart RT, et al: Effects of intravenous injections of nicotine on the circulation. Am Heart J (34): 65, 1947.

  38. Boyle AJ, Clarke NE, Mosher RE, McCann DS: Chelation therapy in circulatory and sclerosing diseases. Fed Proc 20(3) (Part II) (suppl 10):243-257, 1961.

  39. Boyle AS, Mosher LE, McCann DS: Some in vivo effects of chelation-I: Rheumatoid arthritis. J Chronic Dis 16:325, 1963.

  40. Brachet P and Klein C: Cell response to CAMP during aggregation phase of Dictyostelium discoideum. Comparison of the inhibitory effects of progesterone and the stimulatory action of EDTA and ionophore A23187. Differention (8)1:1, 1977.

  41. Brecher A: Bye-Bye Bypass: The Truth About Chelation Therapy. Troup, Texas, Health Savers Press, 1989.

  42. Brien TG and Fay J: [51Cr] EDTA biological half life as an index of renal function. J Nuc Med. (13) 5:339, 1972.

  43. Brecher A: Bye-Bye Bypass: The Truth About Chelation Therapy. Troup, Texas, Health Savers Press, 1989.

  44. Brucknerova O, Tulacek J and Krojzl O: Chelates in the treatment of obliterating arteriopathies. Vnitrni Lek 14:841, 1968.

  45. Brucknerova 0 and Malinovska V: First clinical experience with combined treatment with chelation III and glucagon in ischemic disease of the lower extremities, Cas Lek Cas 119:814,1980.

  46. Brucknerova 0, Tulacek J: Chelates in the treatment of occlusive atherosclerosis. (Czech, Praha) Vnitr Lek 18:729, 1972.

  47. BurckhardIt P, Boillat AM, Reudi B, et al: Effect of parathyroid hormone immunoheterogeneity. Schweiz Med Wochenschr (105) 50:1692, 1975.

  48. Butler AM: Use of calcium ethylenediaminetetraacetate in treating heavy-metal poisoning. Arch Indust Hyg Occupat Med 7:136, 1952.

  49. Butterfield JD, McGraw CP: Free radical pathology. Stroke 9(5):443, 1978.

  50. Calcium disodium edetate and disodium edetate. Drugs for human use; drug efficacy study implementation. Department of Health, Education, and Welfare. Food and Drug Administration. Federal Registrar 35 F.R. 437, 1970.

  51. Casdorph HR: Chelation therapy: a reappraisal. N Z Med J 66, 1983.

  52. Casdorph HR: EDTA chelation therapy, efficacy in arteriosclerotic heart disease. J Holistic Medicine 3(1):53, 1981.

  53. Casdorph HR: EDTA chelation therapy II, efficacy in brain disorders. J Holistic Medicine 3(2):101, 1981.

  54. Casdorph HR, Farr CH: EDTA chelation therapy Ill: Treatment of peripheral arterial occlusion, an alternative to amputation. J Holistic Medicine 3(1):3, 1983.

  55. Cashion WR Jr: What about chelation? Texas Medicine 80:6, 1984.

  56. Castellino N and Aloj S: Effects of calcium sodium ethylenediaminetetra-acetate on the kinetics of the distribution and excretion of lead in the rat. Brit J Indust Med 22:172, 1965.

  57. Catsch A: Radioactive metal mobilization. Fed Proc 20 (Suppl 10):206, 1961.

  58. Catsch A and Harmuth-Hoene AE: Pharmacology and therapeutic applications of agents used in heavy metal poisoning. Pharmac Ther. A, (1):1, 1976.

  59. Chaitlow L: Chelation Therapy: The Revolutionary Alternative to Heart Surgery. San Francisco, Thorsons SF, 1991.

  60. Chantler C and Barratt TM: Estimation of glomerular filtration rate from plasma clearance of 51-chromium edetic acid. Arch Dis Child 47:613, 1972.

  61. Chantler C, Garnett ES, Parsons V and Veall N: Glomerular filtration rate measurement in man by the single injection method using 51Cr-EDTA. Clin Sci 37:169, 1969.

  62. Chappell LT and Stahl JP: The correlation between EDTA chelation therapy and improvement in cardiovascular function: a meta-analysis. J Adv Med 6(3):139, 1993.

  63. Chappell LT, Stahl JP and Evans R: EDTA chelation treatment for vascular disease: a meta-analysis using unpublished data. J Adv Med 7(3),131, 1994.

  64. Chappell LT, Janson M, Whitaker J: A challenge to cardiovascular surgeons. J Adv Med (In Press)

  65. Chappell LT: Chelation therapy, smoking and health care costs (Letter). J Adv Med 7:107, 1994.

  66. Chappell LT: EDTA chelation therapy should be more commonly used in the treatment of vascular disease. Alternative Therapies Health Med 1:53, 1995.

  67. Chappell LT, Miranda R, Rubin M, Carter JP and Trowbridge J: Chelation therapy (Letter). Circulation 92:1350, 1995.

  68. Chelation therapy (Diagnostic and therapeutic technology assessment). JAMA 250:672, 1983.

  69. Chelation therapy: a second look. The Harvard Medical School Health Letter, IX:1, 1984.

  70. Chelation Therapy Clinic: Chelation therapy – the treatment of choice for relief from and prevention of, cardiovascular and age-related diseases. Aukland, New Zealand, The Chelation Therapy Clinic, 1987.

  71. Chelation therapy. Resolution: 66 (I-84). AMA House of Delegates. 1984.

  72. Chelation therapy. Report of the Council on Scientific Affairs. Report F (I-84). AMA House of Delegates. 1984.

  73. Chelation therapy – An informal summary. Department of Health & Human Services. National Institutes of Health. National Heart, Lung, and Blood Institute. Bethesda, Maryland. June 1992.

  74. Chen IW, Park HM, King LR, Bahr GK and Goldsmith RE: Radioimmunoassay of parathyroid hormone: peripheral plasma immunoreactive parathyroid hormone response to ethylenediaminetetraacetate. J Nucl Med 15:763, 1974.

  75. Cheraskin E, Wussow DG, McDonagh EW and Rudolph CJ: Effect of EDTA chelation and supportive multivitamin/trace mineral supplementation with and without physical activity on the heart rate. J InternAcadof Prev Medi 8(6):5, 1984.

  76. Chisolm JJ Jr: Chelation therapy in children with subclinical plumbism. Pediatrics 53:441, 1974.

  77. Chisolm JJ Jr: The use of chelating agents in the treatment of acute and chronic lead intoxication in childhood. J Pediat 73:1, 1968.

  78. Clarke NE Sr, Clarke NE Jr, Mosher RE: Treatment of occlusive vascular disease with disodium ethylene diamine tetraacetic acid (EDTA). The Amer J of the Med Sci June:732, 1960.

  79. Clarke NE, Clarke CN, and Mosher RE: Treatment of angina pectoris with disodium ethylene diamine tetra-acetic acid. Am J of Med Sci 232:654, 1956.

  80. Clarke NE Sr: Atherosclerosis, occlusive vascular disease and EDTA. Am J Cardiol 6(2):233, 1960.

  81. Clarke NE, Clarke CN, Mosher RE: The “in vivo” dissolution of metastatic calcium: An approach to atherosclerosis. Am J Med Sci 229:142,1955.

  82. Cockcroft DW, Gault MH: Prediction of creatinine clearance from serum creatinine. Nephron 16:31, 1976.

  83. Cohen SH, Gong JK and Fishler MC: Ethylene diamine tetraacetic acid (EDTA) treatment of internal radioactive contamination. Nucleonics (11)1: 56, 1953.

  84. Cohen S, Weissler AM and Schoenfeld CD: Antagonism of the contractile effect of digitalis by EDTA in the normal human ventricle. Am Heart J 69:502, 1965.

  85. Cook JD, Finch CA, Smith NJ: Evaluation of the iron status of a population. Blood 48(3):449, 1976.

  86. Couric JM: Chelation therapy overdone. FDA Consumer 16:28. 1982.

  87. Cranton EM and Frackelton JP: Negative Danish Study of EDTA chelation biased. Townsend Letter for Doctors July, 604-605, Letter, 1992.

  88. Cranton EM: Critique of the American Medical Association’s published position on hair analysis. J Holistic Medicine 8(1);47, 1986.

  89. Cranton EM, Bland JS, Chatt A, Krakovitz R, Wright JV: Standardization and interpretation of human hair for elemental concentrations. J Holistic Medicine 1982;4:10, 1982.

  90. Cranton EM: Update on hair analysis in clinical medicine. J Holistic Medicine 7(2):120,1986.

  91. Cranton EM and Frackelton JP: The current status of EDTA chelation therapy in the treatment of occlusive arterial disease. Journal of Holistic Medicine 4: 24, 1982.

  92. Cranton EM: Protocol of the American College of Advancement in Medicine for the safe and effective administration of EDTA chelation therapy. J Adv Med 2:269, 1989.

  93. Cranton EM: A textbook on EDTA chelation therapy. J Adv Med 2:1-416, 1989.

  94. Cranton EM and Frackelton JP: Free radical pathology in age associated diseases; treatment with EDTA chelation, nutrition and antioxidants. J Holistic Med 6: 1, 1984.

  95. Cranton EM: Kidney effects of ethylene diamine tetraacetic acid (EDTA): A literature review. J Holistic Medicine 4:152, 1982.

  96. Cranton EM: The current status of EDTA chelation therapy, editorial. J Holistic Med 7(1):3, 1985.

  97. Cranton EM, Brecher A: Bypassing Bypass: The New Technique of Chelation Therapy ed 2 ,Medex Publishers Inc, P.O. Box 44, Trout Dale, VA 24378, 1989.

  98. Craven, PC and Morelli HF: Chelation therapy. West J Med, 122:277, 1975.

  99. Curran CL: Metal chelating agents and hepatic cholesterol synthesis. Proc Soc Exper Biol & Med 88:101, 1955.

  100. Darwish NM and Kratzer FH: Metabolism of ethylenediaminetetraacetic acid (EDTA) by chickens. J Nutr 86:187, 1965.



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  2. Davis FA, Becker FO, Michael JA and Sorensen E: Effect of intravenous sodium bicarbonate disodium EDTA and hyperventilation on visual and oculomotor signs in multiple sclerosis. J Neurol Neuro-surg Psychiat 33:723, 1970.

  3. Davis PS and Deller DJ: Effect of orally administered chelating agents EDTA, DTPA and fructose on radioiron absorption in man. Aust Ann Med 16:70, 1967.

  4. Davis H and Moe PJ: Favorable response of calcinosis universalis to edathamil disodium. Pediatriacs 24:780, 1959.

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  8. Demopoulos, HB: Control of free radicals in the biologic systems. Fed Proc 32: 1903, 1973.

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  10. Demopoulos HB, Flamm ES, Pietronigro DD, Seligman ML: The free radical pathology and the microcirculation in the major central nervous system disorders. Acta Physiol Scand 492(suppl):91, 1980.

  11. Demopoulus HB: Molecular oxygen in health and disease. Presented AAMP Tenth Annual Spring Meeting May 21, 1983, Los Angeles, California.

  12. Demopoulos HB, Peitronigro DD, Seligman ML: The development of secondary pathology with free radical reactions as a threshold mechanism. J Am Coll Tox 2(3):173, 1983.

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  17. Donald GF, Hunter GA, Roman W and Taylor AEJ: Current concepts of cutaneous porphyria and its treatment with particular reference to the use of sodium calcium-edetate. Brit J Derm 82:70, 1970.

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  53. Frackelton JP: Monitoring renal function during EDTA chelation therapy. J Holistic Med 8(1):33, 1986.

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  56. Fuleihan FJD, Kurban AK, Abboud RT, Beidas-jubran N and Farah FS: An objective evaluation of the treatment of systemic scleroderma with disodium EDTA, pyridoxine and reserpine. Brit J Derm 80:184, 1968.

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  60. Ghiringhelli L, Marinoni E and Respighi E: Study of the parathyroid function by means of the Kaiser &Ponsold test in a group of thyroidectomized patients. Minerva Med 54:2829, 1963.

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  65. Goetzl EJ: Oxygenation products of arachidonic acid as mediators of hypersensitivity and inflammation. Med Clin North Am 65(4):809, 1981.

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